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Gene Expression Data
Assay Details
Assay
Reference: J:215514 Saulnier A, et al., The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
Assay type: RNA in situ
MGI Accession ID: MGI:7522279
Gene symbol: Reln
Gene name: reelin
Probe: Reelin probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S7A rostral Dmrt5+/+: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex marginal zone Cajal-Retzius cell Present S7A rostral left

Specimen S7A rostral Dmrt5-/-: embryonic day 18.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex Cajal-Retzius cell Weak Regionally restricted S7A rostral right A few positive cells remained in the most medial portion of the mutant cortex. Some immunopositive cells also accumulated in the form of aggregates at the border between the neocortex and the piriform cortex.

Specimen S7A caudal Dmrt5+/+: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex marginal zone Cajal-Retzius cell Present S7A caudal left

Specimen S7A caudal Dmrt5-/-: embryonic day 18.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex Cajal-Retzius cell Weak Regionally restricted S7A caudal right A few positive cells remained in the most medial portion of the mutant cortex.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory