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Gene Expression Data
Assay Details
Assay
Reference: J:215514 Saulnier A, et al., The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
Assay type: RNA in situ
MGI Accession ID: MGI:7522037
Gene symbol: Hes5
Gene name: hes family bHLH transcription factor 5
Probe: Hes5 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6J Dmrt5+/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 6J Dmrt5+/+ Expression domain was in the dorsomedial region.

Specimen 6J Dmrt5-/-: embryonic day 12.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Weak Regionally restricted 6J Dmrt5-/- Expression was downregulated in the mutant compared with wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory