About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:215514 Saulnier A, et al., The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
Assay type: RNA in situ
MGI Accession ID: MGI:7522018
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5C sagittal Dmrt5+/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 5C Dmrt5+/+ top

Specimen 5C sagittal Dmrt5-/-: embryonic day 12.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 5C Dmrt5-/- top Expression was upregulated in the medial and posterior cortical anlage of the mutant compared to controls.

Specimen 5C coronal Dmrt5+/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present 5C Dmrt5+/+ bottom

Specimen 5C coronal Dmrt5-/-: embryonic day 12.5; Dmrta2tm1Ejbd/Dmrta2tm1Ejbd (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 5C Dmrt5-/- bottom Expression was upregulated in the medial and posterior cortical anlage of the mutant compared to controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/28/2026
MGI 6.24
The Jackson Laboratory