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Tg(CMV-cat,-SDHA*Y215F)1Hom
Transgene Detail
Summary
Symbol: Tg(CMV-cat,-SDHA*Y215F)1Hom
Name: transgene insertion 1, Yoshimi Homma
MGI ID: MGI:7520826
Transgene: Tg(CMV-cat,-SDHA*Y215F)1Hom  Location: unknown  
Alliance: Tg(CMV-cat,-SDHA*Y215F)1Hom page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene contains Cytomegalovirus CMV promoter, rabbit beta globin intron, Phage P1 loxP sites, E. coli chloramphenicol acetyltransferase (CAT) gene, rabbit beta globin polyA, human SDHA gene cDNA, FLAG epitope tag(synthetic), and pA. (J:246252)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:246252 Ogura M, et al., Mitochondrial reactive oxygen species suppress humoral immune response through reduction of CD19 expression in B cells in mice. Eur J Immunol. 2017 Feb;47(2):406-418
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory