Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Tff2-Hbegf,-cre/ERT2)#Tcw
Name:	transgene insertion, Timothy C Wang
MGI ID:	MGI:7520440
Synonyms:	Tff2-DTR-CreERT2
Transgene:	Tg(Tff2-Hbegf,-cre/ERT2)#Tcw  Location: unknown
Alliance:	Tg(Tff2-Hbegf,-cre/ERT2)#Tcw page

Strain of Origin:

CBA x C57BL/6J

Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Tff2-Hbegf,-cre/ERT2)#Tcw expresses 1 gene Transgene expresses: Organism Expressed Gene Note Not Specified Hbegf   Tg(Tff2-Hbegf,-cre/ERT2)#Tcw expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Tff2 (MGI:1306805)   Mutation details: Using recombineering methods, the DTR-CreERT2-FrtNeoFrt cassette was inserted at the ATG codon in exon 1 of the Tff2 gene in the BAC RP24-335C16. The modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. The modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:338908)

Activity:	Tissue activity of this recombinase allele
Driver:	Tff2 (mouse) Summary of all recombinase alleles driven by Tff2. Comparative matrix view of recombinase activities Alliance mouse Tff2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:338908 Jiang Z, et al., Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis. Cell Stem Cell. 2023 Aug 3;30(8):1091-1109.e7
All:	1 reference(s)