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Gene Expression Data
Assay Details
Assay
Reference: J:167262 Sumida H, et al., LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis. Blood. 2010 Dec 2;116(23):5060-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7520002
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-Pecam1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Knock-outs were either female Lpar4<tm1Sati>/Lpar4<tm1Sati> or male Lpar4<tm1Sati>/Y. Both have been annotated.
Results
Specimen 6A: embryonic day 14.5 (more )
Note: Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS22: artery endothelium Present 6A
TS22: blood vessel endothelium Present 6A
TS22: carotid artery Present 6A
TS22: jugular vein Present 6A
TS22: subclavian artery Present 6A
TS22: subclavian vein Present 6A
Specimen 6B Female: embryonic day 14.5; Lpar4tm1Sati/Lpar4tm1Sati (more )
Note: This mutant is apparently normal. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS22: artery endothelium Present 6B
TS22: blood vessel endothelium Present 6B
TS22: carotid artery Present 6B
TS22: jugular vein Present 6B
TS22: subclavian artery Present 6B
TS22: subclavian vein Present 6B
Specimen 6B Male: embryonic day 14.5; Lpar4tm1Sati/Y (more )
Note: This mutant is apparently normal.
Structure Level Pattern Image Note
TS22: artery endothelium Present
TS22: blood vessel endothelium Present
TS22: carotid artery Present
TS22: jugular vein Present
TS22: subclavian artery Present
TS22: subclavian vein Present
Specimen 6C Female: embryonic day 14.5; Lpar4tm1Sati/Lpar4tm1Sati (more )
Note: This mutant is edematous. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS22: artery endothelium Present 6C
TS22: blood vessel endothelium Present 6C
TS22: carotid artery Present 6C
TS22: jugular vein Present 6C
TS22: subclavian artery Present 6C
TS22: subclavian vein Present 6C
Specimen 6C Male: embryonic day 14.5; Lpar4tm1Sati/Y (more )
Note: This mutant is edematous.
Structure Level Pattern Image Note
TS22: artery endothelium Present
TS22: blood vessel endothelium Present
TS22: carotid artery Present
TS22: jugular vein Present
TS22: subclavian artery Present
TS22: subclavian vein Present
Specimen 6E: embryonic day 18.5 (more )
Note: Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present 6E
TS26: small intestine vascular element Present 6E
Specimen 6F Female: embryonic day 18.5; Lpar4tm1Sati/Lpar4tm1Sati (more )
Note: This mutant is apparently normal. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present 6F
TS26: small intestine vascular element Present 6F
Specimen 6F Male: embryonic day 18.5; Lpar4tm1Sati/Y (more )
Note: This mutant is apparently normal.
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present
TS26: small intestine vascular element Present
Specimen 6G Female: embryonic day 18.5; Lpar4tm1Sati/Lpar4tm1Sati (more )
Note: This mutant is edematous. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present 6G Blood vessels appeared normal in this mutant compared to wild-type.
TS26: small intestine vascular element Present 6G Blood vessels appeared normal in this mutant compared to wild-type.
Specimen 6G Male: embryonic day 18.5; Lpar4tm1Sati/Y (more )
Note: This mutant is edematous.
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present Blood vessels appeared normal in this mutant compared to wild-type.
TS26: small intestine vascular element Present Blood vessels appeared normal in this mutant compared to wild-type.
Specimen 6H: embryonic day 18.5 (more )
Note: Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present 6H
Specimen 6I Female: embryonic day 18.5; Lpar4tm1Sati/Lpar4tm1Sati (more )
Note: This mutant is apparently normal. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present 6I
Specimen 6I Male: embryonic day 18.5; Lpar4tm1Sati/Y (more )
Note: This mutant is apparently normal.
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present
Specimen 6J Female: embryonic day 18.5; Lpar4tm1Sati/Lpar4tm1Sati (more )
Note: This mutant is edematous. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present 6J
Specimen 6J Male: embryonic day 18.5; Lpar4tm1Sati/Y (more )
Note: This mutant is edematous.
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present
Specimen S3A: embryonic day 18.5 (more )
Note: Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present S3A , S3D
TS26: lung vascular element Present S3A , S3D
Specimen S3E Female: embryonic day 18.5; Lpar4tm1Sati/Lpar4tm1Sati (more )
Note: This mutant is apparently normal. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present S3H , S3E This mutant had enlarged lymphatics as compared to wild-type embryos.
TS26: lung vascular element Present S3H , S3E This mutant had enlarged lymphatics as compared to wild-type embryos.
Specimen S3E Male: embryonic day 18.5; Lpar4tm1Sati/Y (more )
Note: This mutant is apparently normal.
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present This mutant had enlarged lymphatics as compared to wild-type embryos.
TS26: lung vascular element Present This mutant had enlarged lymphatics as compared to wild-type embryos.
Specimen S3I Female: embryonic day 18.5; Lpar4tm1Sati/Lpar4tm1Sati (more )
Note: This mutant is edematous. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:7520054).
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present S3L , S3I This mutant had enlarged lymphatics as compared to wild-type embryos.
TS26: lung vascular element Present S3L , S3I This mutant had enlarged lymphatics as compared to wild-type embryos.
Specimen S3I Male: embryonic day 18.5; Lpar4tm1Sati/Y (more )
Note: This mutant is edematous.
Structure Level Pattern Image Note
TS26: blood vessel endothelium Present This mutant had enlarged lymphatics as compared to wild-type embryos.
TS26: lung vascular element Present This mutant had enlarged lymphatics as compared to wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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