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Gene Expression Data
Assay Details
Assay
Reference: J:58028 Russo MA, et al., Spatiotemporal patterns of expression of neurotrophins and neurotrophin receptors in mice suggest functional roles in testicular and epididymal morphogenesis. Biol Reprod. 1999 Oct;61(4):1123-32
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7518996
Gene symbol: Ngfr
Gene name: nerve growth factor receptor (TNFR superfamily, member 16)
Antibody: anti-p75
Detection system: Secondary antibody
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: interstitium of the testis Strong Widespread 1A Strong expression in entire population of mesenchymal cells spread through interstitial tissue outlining developing testicular cords.
TS20: primary sex cord Absent 1A No expression in cord cells.
TS20: mesonephros mesenchyme Present 1A Expression in mesonephric mesenchyme.
Specimen 1B: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: interstitium of the testis Strong Regionally restricted 1B High levels of expression persisted around testicular cords until P1. Co-expression with Acta2 in inner layers of mesenchyme.
Specimen 1C: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: interstitium of the testis Present 1C Intensity of expression over mesenchymal cells progressively declined during postnatal development.
Specimen 1D: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: interstitium of the testis Absent 1D Expression undetectable at puberty.
Specimen 5A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: male reproductive system mesenchyme Present Regionally restricted 5A Expression in thick layer of mesenchymal cells surrounding mesonephric duct.
Specimen 5C: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: epididymis Present Regionally restricted 5C Expression generally strong close to epididymal duct and less intense in surroudning intersititial tissue.
Specimen 5E: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: epididymis Present 5E Expression gradually decreases with age.
Specimen 5F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epididymis Absent 5F Expression undetectable in adult.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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