Gene Expression Data
Assay Details
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Assay
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Reference:
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J:338204
Luzzio A, et al., The spontaneous mouse mutant low set ears (Lse) is caused by tandem duplication of Fgf3 and Fgf4. Mamm Genome. 2023 Jun 21;
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7516394
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Gene symbol:
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Fgf3
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Gene name:
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fibroblast growth factor 3
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Probe:
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Fgf3 probe
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Probe preparation:
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labelled with digoxigenin
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Results
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Specimen
4a:
embryonic day 10.5; Dsht/Dsht +
(more  )
Specimen
4a:
(close  )
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Genetic Background:
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involves: C57BL/6J * C3H/HeJ
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Mutant Allele(s):
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Dsht/Dsht+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
4b:
embryonic day 10.5; Lse/Lse +
(more )
Specimen
4b:
(close )
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Genetic Background:
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B6C3Fe a/a-Lse/J
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Mutant Allele(s):
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Lse/Lse+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: otocyst |
Weak |
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4b'
,
4b
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Expression in otic vesicle similar to control.
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| TS17: 2nd branchial arch |
Strong |
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4b'
,
4b
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Ectopic expression with highly increased expression levels in second branchial arch.
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| TS17: embryo |
Present |
Regionally restricted |
4b
,
4b''
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Ectopic expression adjacent fo forelimb.
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| TS17: urogenital ridge |
Strong |
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4b
,
4b''
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Robust ectopic expression in urogenital ridge.
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Specimen
4c:
embryonic day 10.5; Lse/ Lse
(more )
Specimen
4c:
(close )
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Genetic Background:
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B6C3Fe a/a-Lse/J
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Mutant Allele(s):
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Lse/Lse
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: otocyst |
Weak |
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4c'
,
4c
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| TS17: 2nd branchial arch |
Strong |
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4c
,
4c'
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Much higher expression levels than in Lse/+ embryos.
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| TS17: 1st branchial arch |
Present |
Regionally restricted |
4c'
,
4c
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Some expansion of expression domain into first branchial arch.
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| TS17: embryo |
Strong |
Regionally restricted |
4c''
,
4c
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Higher levels of ectopic expression adjacent fo forelimb.
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| TS17: urogenital ridge |
Strong |
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4c''
,
4c
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Higher levels of expression in urogenital ridge.
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Analysis Tools
