About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:62777 Obata J, et al., p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos. Genes Cells. 2001 Apr;6(4):345-60
Assay type: RNA in situ
MGI Accession ID: MGI:7514096
Gene symbol: Ptf1a
Gene name: pancreas specific transcription factor, 1a
Probe: p48 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3A Expression is as a thin stripe to the posterior end of the neural tube.
TS17: hindbrain Present Regionally restricted 3A Expression is absent anterior to the myelencephalon (the anterior limit of expression is at the lower end of the rhombic lip) and is weak around the otic vesicle.
TS17: tail neural tube Present 3A
TS17: visceral organ system Weak Regionally restricted 3A Expression is as two small dots near the hepatic primordia.
TS17: dorsal root ganglion Absent 3A
TS17: peripheral nervous system ganglion Absent 3A

Specimen 3B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3B Expression is as a thin stripe to the posterior end of the neural tube.
TS17: tail neural tube Present 3B
TS17: dorsal root ganglion Absent 3B

Specimen 3C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: cerebellum primordium Present 3C
TS20: dorsal root ganglion Absent 3C
TS20: peripheral nervous system ganglion Absent 3C

Specimen 3D: embryonic day 9.5 (more )
Note: This section is at the cervical level.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3D Expression is in a narrow area slightly dorsal to the dorso-ventral border.

Specimen 3E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 3E Expression is in an area slightly dorsal to the dorso-ventral border and expands dorsally and is strongest in the ventricular zone.
TS17: neural tube roof plate Absent 3E

Specimen 3F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: pancreas primordium dorsal bud Present 3F
TS15: pancreas primordium ventral bud Present 3F

Specimen 3G: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: metencephalon alar plate ventricular layer Present 3G

Specimen not shown E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Absent

Specimen not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted Expression is in the myelencephalon.
TS15: neural tube Present Regionally restricted Expression is at the cervical level.
TS15: dorsal root ganglion Absent
TS15: peripheral nervous system ganglion Absent

Specimen not shown E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube Present Regionally restricted Expression is as a thin stripe to the posterior end of the neural tube.
TS19: myelencephalon lateral wall Present Regionally restricted Expression is absent anterior to the myelencephalon and is weak around the otic vesicle.
TS19: tail neural tube Present
TS19: dorsal root ganglion Absent
TS19: peripheral nervous system ganglion Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory