About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:92062 Pratt T, et al., The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse. Development. 2004 Aug;131(15):3773-84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7514063
Gene symbol: Efnb2
Gene name: ephrin B2
Results
Specimen 5A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: neural retina Present Graded 5A Dorsolateral (high) to ventrolateral (low) gradient of expression, with strongest expression dorsolaterally.
TS21: optic nerve Weak 5A Weak expression in optic nerve.

Specimen 5B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: neural retina Present Graded 5B Gradient remains at E16.5 in both wild-type and mutant.
TS24: optic nerve Weak 5B Weak expression in optic nerve.

Specimen 5C: embryonic day 13.5; Foxg1tm1(cre)Skm/Foxg1tm1(cre)Skm (more )
Structure Level Pattern Image Note
TS21: neural retina Present Graded 5C Dorsal (high) to ventral (low) gradient of expression.

Specimen 5D: embryonic day 16.5; Foxg1tm1(cre)Skm/Foxg1tm1(cre)Skm (more )
Structure Level Pattern Image Note
TS24: neural retina Present Graded 5D Strongest expression in dorsolateral retina.

Specimen 6A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present 6A Expression is most widespread in more dorsal structures in developing forebrain and eye.
TS21: eye Present 6A Expression is most widespread in more dorsal structures in developing forebrain and eye.
TS21: hypothalamus Present Regionally restricted 6A Expression in ventral hypothalamic midline.

Specimen 6B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hypothalamus Present Regionally restricted 6B Expression in ventral hypothalamic midline.

Specimen 6C: embryonic day 13.5; Foxg1tm1(cre)Skm/Foxg1tm1(cre)Skm (more )
Structure Level Pattern Image Note
TS21: telencephalon Present 6C
TS21: hypothalamus Present Regionally restricted 6C Expression in hypothalamic midline.

Specimen 6D: embryonic day 13.5; Foxg1tm1(cre)Skm/Foxg1tm1(cre)Skm (more )
Structure Level Pattern Image Note
TS21: hypothalamus Present Regionally restricted 6D Expression in hypothalamic midline.

Specimen 6E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: optic chiasma Present Regionally restricted 6E Expression at optic chiasm where expressing cells contact optic nerve.

Specimen 6F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: optic chiasma Present Regionally restricted 6F Expression at optic chiasm where expressing cells contact optic nerve.

Specimen 6G: embryonic day 16.5; Foxg1tm1(cre)Skm/Foxg1tm1(cre)Skm (more )
Structure Level Pattern Image Note
TS24: optic chiasma Present Regionally restricted 6G Expression persists at mutant chiasm where it contacts Ephb2-expressing axons.

Specimen 6H: embryonic day 16.5; Foxg1tm1(cre)Skm/Foxg1tm1(cre)Skm (more )
Structure Level Pattern Image Note
TS24: optic chiasma Present Regionally restricted 6H Expression persists at mutant chiasm where it contacts Ephb2-expressing axons.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory