Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tmem119em1(cre)Mari
Name:	transmembrane protein 119; endonuclease-mediated mutation 1, Thomas Marichal
MGI ID:	MGI:7513910
Synonyms:	Tmem119Cre
Gene:	Tmem119  Location: Chr5:113931790-113938530 bp, - strand  Genetic Position: Chr5, 55.55 cM
Alliance:	Tmem119em1(cre)Mari page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (other) (Recombinase) Mutation:    Insertion   Tmem119em1(cre)Mari expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tmem119 (MGI:2385228)   Mutation details: Using CRISPR/Cas9-mediated genome engineering, a Cre-polyA cassette was introduced in the Tmem119 gene upstream of the ATG start codon. (J:338559)

Activity:	Tissue activity of this recombinase allele
Driver:	Tmem119 (mouse) Summary of all recombinase alleles driven by Tmem119. Alliance mouse Tmem119 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem119 Mutation:	25 strains or lines available

Original:	J:338559 Vanneste D, et al., MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation. Nat Immunol. 2023 May;24(5):827-840
All:	1 reference(s)