Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Dcxem1(cre/ERT2)Jjan
Name:	doublecortin; endonuclease-mediated mutation 1, Joanna Jankowsky
MGI ID:	MGI:7513054
Gene:	Dcx  Location: ChrX:142638838-142716307 bp, - strand  Genetic Position: ChrX, 64.89 cM
Alliance:	Dcxem1(cre/ERT2)Jjan page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Dcxem1(cre/ERT2)Jjan expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Dcx (MGI:1277171)   Mutation details: CRISPR/cas9 genome editing is used to insert an in-frame T2A ribosome skipping sequence and Cre recombinase/ERT2 fusion immediately following the final M366 residue in exon 7. The inserted sequence is not expected to affect expression of Dcx. (J:343514)

Activity:	Tissue activity of this recombinase allele
Driver:	Dcx (mouse) Summary of all recombinase alleles driven by Dcx. Alliance mouse Dcx gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dcx Mutation:	18 strains or lines available

Original:	J:343514 Perez GA, et al., Generation of a Dcx-CreER(T2) knock-in mouse for genetic manipulation of newborn neurons. Genesis. 2023 Dec 16;:e23584
All:	1 reference(s)