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Gene Expression Data
Assay Details
Assay
Reference: J:338018 Stathopoulou A, et al., CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression. Cardiovasc Res. 2023 Apr 13;
Assay type: RNA in situ
MGI Accession ID: MGI:7513000
Gene symbol: Tbx1
Gene name: T-box 1
Results
Specimen S5A,A': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Present S5A , S5A'
TS15: outflow tract Present S5A , S5A'
TS15: secondary heart field Present S5A , S5A'
TS15: pharynx mesenchyme Present Regionally restricted S5A' , S5A Expression in multilineage progenitor cells localized in lateral part of caudal pharyngeal mesoderm, adjacent of 4th branchial arch.
Specimen S5B,B': embryonic day 9.5; Chd7tm2a(EUCOMM)Wtsi/Chd7tm2a(EUCOMM)Wtsi, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: branchial arch Present S5B , S5B' Spatial distribution and level of expression in branchial arches, outflow tract or second heart field similar to that of control.
TS15: outflow tract Present S5B , S5B' Spatial distribution and level of expression in branchial arches, outflow tract or second heart field similar to that of control.
TS15: secondary heart field Present S5B , S5B' Spatial distribution and level of expression in branchial arches, outflow tract or second heart field similar to that of control.
TS15: pharynx mesenchyme Present Regionally restricted S5B' , S5B No alteration of expression in multilineage progenitor cells compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory