Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tbx21em1(flpo)Saka
Name:	T-box 21; endonuclease-mediated mutation 1, Masahiro Yamamoto
MGI ID:	MGI:7511834
Synonyms:	Tbx21-Flp
Gene:	Tbx21  Location: Chr11:96988897-97006157 bp, - strand  Genetic Position: Chr11, 60.95 cM, cytoband D
Alliance:	Tbx21em1(flpo)Saka page

Strain of Origin:

C57BL/6N

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Tbx21em1(flpo)Saka expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tbx21 (MGI:1888984)   Mutation details: CRISPR-targeting inserted a P2A peptide sequence containing mammalian codon-optimized Flp recombinase cDNA just before the stop codon of Tbx21 in the exon6. (J:338342)

Activity:	Tissue activity of this recombinase allele
Driver:	Tbx21 (mouse) Summary of all recombinase alleles driven by Tbx21. Alliance mouse Tbx21 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx21 Mutation:	36 strains or lines available

Original:	J:338342 Okamoto M, et al., A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity. Cell Rep. 2023 Jul 12;42(7):112813
All:	1 reference(s)