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Gene Expression Data
Assay Details
Assay
Reference: J:337971 Kohler TN, et al., Plakoglobin is a mechanoresponsive regulator of naive pluripotency. Nat Commun. 2023 Jul 7;14(1):4022
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7511753
Gene symbol: Jup
Gene name: junction plakoglobin
Results
Specimen 4a E2.5: embryonic day 2.5 (more )
Note: Triple labeled: green - Jup; magenta - Sox17 (assay MGI:7511755); white - Sox2 (assay MGI:7511754).
Structure Level Pattern Image Note
TS3: compacted morula Absent 4a E2.5 (upper) , 4a E2.5 (lower)
Specimen 4a E3.5: embryonic day 3.5 (more )
Note: Triple labeled: green - Jup; magenta - Sox17 (assay MGI:7511755); white - Sox2 (assay MGI:7511754).
Structure Level Pattern Image Note
TS4: blastocyst Present Regionally restricted 4a E3.5 (lower) , 4a E3.5 (upper) Expression in epiblast coincides with emergence of naive pluripotency in pre-implantation epiblast.
Specimen 4a E4.5: embryonic day 4.5 (more )
Note: Triple labeled: green - Jup; magenta - Sox17 (assay MGI:7511755); white - Sox2 (assay MGI:7511754).
Structure Level Pattern Image Note
TS5: blastocyst Present Regionally restricted 4a E4.5 (upper) , 4a E4.5 (lower) Expression in epiblast coincides with emergence of naive pluripotency in pre-implantation epiblast.
Specimen 4b E5.5: embryonic day 5.5 (more )
Note: Double labeled: green - Jup; white - Sox17 (assay MGI:7511755).
Structure Level Pattern Image Note
TS7: extraembryonic ectoderm Present 4b E5.5 (upper) , 4b E5.5 (lower) Expression restricted to extraembryonic ectoderm.
TS7: epiblast Absent 4b E5.5 (upper) , 4b E5.5 (lower) Expression completely absent in epiblast at E5.5.
Specimen 4b E6.5: embryonic day 6.5 (more )
Note: Double labeled: green - Jup; white - Sox17 (assay MGI:7511755).
Structure Level Pattern Image Note
TS8: epiblast Absent 4b E6.5 (upper) , 4b E6.5 (lower)
Specimen 4e (upper): embryonic day 4.25 (more )
Note: Triple labeled: green - Jup; magenta - Pou5f1 (assay MGI:7511757); white - Sox17 (assay MGI:7511755).
Structure Level Pattern Image Note
TS5: blastocyst Present Regionally restricted 4e (upper right) , 4e (upper left) Expression in primitive endoderm cells once sorted to inner cell mass surface.
Specimen 4e (lower): embryonic day 4.25 (more )
Note: Triple labeled: green - Jup; magenta - Pou5f1 (assay MGI:7511757); white - Sox17 (assay MGI:7511755).
Structure Level Pattern Image Note
TS5: blastocyst Present Regionally restricted 4e (lower right) , 4e (lower left) Expression in primitive endoderm cells once sorted to inner cell mass surface.
Specimen S4e (upper): embryonic day 4.25 (more )
Note: Triple labeled: green - Jup; magenta - Pou5f1 (assay MGI:7511757); white - Sox17 (assay MGI:7511755).
Structure Level Pattern Image Note
TS5: blastocyst Present Regionally restricted S4e (upper) Expression in primitive endoderm cells once sorted to inner cell mass surface.
Specimen S4e (middle): embryonic day 4.25 (more )
Note: Triple labeled: green - Jup; magenta - Pou5f1 (assay MGI:7511757); white - Sox17 (assay MGI:7511755).
Structure Level Pattern Image Note
TS5: blastocyst Present Regionally restricted S4e (middle) Expression in primitive endoderm cells once sorted to inner cell mass surface.
Specimen S4e lower): embryonic day 4.25 (more )
Note: Triple labeled: green - Jup; magenta - Pou5f1 (assay MGI:7511757); white - Sox17 (assay MGI:7511755).
Structure Level Pattern Image Note
TS5: blastocyst Present Regionally restricted S4e (lower) Expression in primitive endoderm cells once sorted to inner cell mass surface.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory