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Gene Expression Data
Assay Details
Assay
Reference: J:175773 Maxwell MM, et al., The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS. Hum Mol Genet. 2011 Oct 15;20(20):3986-96
Assay type: Western blot
MGI Accession ID: MGI:7511743
Gene symbol: Sirt2
Gene name: sirtuin 2
Antibody: Anti-Sirt2 S8447
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 4A
 Sample Information Bands Other Sample Information
Lane AgeStructure 43 kDa (a) 39 kDa (b) 36 kDa (c) Genetic BackgroundMutant Allele(s)Sex
4 months P m 4 TS28: spinal cord Present Very strong Weak C57BL/6J Not Specified
4 months P m 4 TS28: spinal cord Present Very strong Weak C57BL/6J Not Specified
4 months P m 4 TS28: spinal cord Present Very strong Weak C57BL/6J Not Specified
4 months P m 4 TS28: spinal cord Present Very strong Weak C57BL/6J Not Specified
4 months P m 4 TS28: spinal cord Present Very strong Weak C57BL/6J Not Specified
19 months P m 19 TS28: spinal cord Present Very strong Present C57BL/6J Not Specified
19 months P m 19 TS28: spinal cord Present Very strong Present C57BL/6J Not Specified
19 months P m 19 TS28: spinal cord Present Very strong Present C57BL/6J Not Specified
19 months P m 19 TS28: spinal cord Present Very strong Present C57BL/6J Not Specified
Notes:
(a) Sirt2.1 isoform. No age-dependent expression level changes were noted.
(b) Sirt2.2 isoform. No age-dependent expression level changes were noted.
(c) Sirt2.3 isoform. Prolonged exposure illustrated differences in the less-abundant isoform. Sirt2.3 represented a fraction of the total amount of Sirt2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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