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Gene Expression Data
Assay Details
Assay
Reference: J:191149 Alves CH, et al., Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Hum Mol Genet. 2013 Jan 1;22(1):35-50
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7511557
Gene symbol: Ptprc
Gene name: protein tyrosine phosphatase receptor type C
Antibody: Anti-CD45-PE (12-0151)
Detection system: other - see notes
Assay notes: The antibody was conjugated with phycoerythrin (PE).
Results
Specimen S6C: postnatal month 3; Crb2tm1.1Wij/? (more )
Note: Controls could be Crb2F/F or Crb2F/+/Chx10Cre+/-.
Structure Cell Type Level Pattern Image Note
TS28: retina microglial cell Present S6C
Specimen S6D: postnatal month 3; Crb2tm1.1Wij/Crb2tm1.1Wij, Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: retina microglial cell Present S6D At 3 months, staining of activated microglia cells was increased in the mutant compared with control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory