Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Myh6em2(cre)Smoc
Name:	myosin, heavy polypeptide 6, cardiac muscle, alpha; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
MGI ID:	MGI:7510097
Synonyms:	Myh6-Cre, Myh6em(Cre)1Smoc
Gene:	Myh6  Location: Chr14:55179378-55204384 bp, - strand  Genetic Position: Chr14, 28.01 cM
Alliance:	Myh6em2(cre)Smoc page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Myh6em2(cre)Smoc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Myh6 (MGI:97255)   Mutation details: The CRISPR/Cas9 technology was used to insert the internal ribosome entry site (IRES)-Cre cassette, the woodchuck hepatitis virus posttranscriptional regulatory element (wpre), and a polyA sequence between the translational stop codon and the 3' UTR of the endogenous Myh6 gene. (J:337240)

Activity:	Tissue activity of this recombinase allele
Driver:	Myh6 (mouse) Summary of all recombinase alleles driven by Myh6. Comparative matrix view of recombinase activities Alliance mouse Myh6 gene page

In Mice Carrying this Mutation:

29 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myh6 Mutation:	206 strains or lines available

Original:	J:337240 Huang X, et al., Generation and characterization of a Myh6-driven Cre knockin mouse line. Transgenic Res. 2021 Dec;30(6):821-835
All:	2 reference(s)