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Gene Expression Data
Assay Details
Assay
Reference: J:221937 Watson JA, et al., Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS. PLoS Genet. 2015 Jun;11(6):e1005290
Assay type: Western blot
MGI Accession ID: MGI:7509983
Gene symbol: Hgs
Gene name: HGF-regulated tyrosine kinase substrate
Antibody: anti-HRS
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Image: 2B HGS ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
Brain wt P w 4 TS28: brain Strong (a) involves: C57BL/6J Not Specified
Brain tn P w 4 TS28: brain Weak (b) B6.C3-Hgstn Hgstn/HgstnNot Specified
Heart wt P w 4 TS28: heart Trace involves: C57BL/6J Not Specified
Heart tn P w 4 TS28: heart Trace (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
Kidney wt P w 4 TS28: metanephros Trace involves: C57BL/6J Not Specified
Kidney tn P w 4 TS28: metanephros Trace (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
Liver wt P w 4 TS28: liver Present involves: C57BL/6J Not Specified
Liver tn P w 4 TS28: liver Present (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
Spinal cord wt P w 4 TS28: spinal cord Strong (a) involves: C57BL/6J Not Specified
Spinal cord tn P w 4 TS28: spinal cord Weak (d) B6.C3-Hgstn Hgstn/HgstnNot Specified
Lung wt P w 4 TS28: lung Present involves: C57BL/6J Not Specified
Lung tn P w 4 TS28: lung Present (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
Muscle wt P w 4 TS28: muscle tissue Trace involves: C57BL/6J Not Specified
Muscle tn P w 4 TS28: muscle tissue Trace (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
Spleen wt P w 4 TS28: spleen Trace involves: C57BL/6J Not Specified
Spleen tn P w 4 TS28: spleen Trace (c) B6.C3-Hgstn Hgstn/HgstnNot Specified
Notes:
(a) High levels of expression in nervous system.
(b) Significant reduction of expression compared to wild type.
(c) Authors report expression differentially affected in non-neuronal tissues.
(d) Significantly reduced expression compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory