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Gene Expression Data
Assay Details
Assay
Reference: J:127123 Barker N, et al., Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature. 2007 Oct 25;449(7165):1003-7
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7509962
Gene symbol: Lgr5
Gene name: leucine rich repeat containing G protein coupled receptor 5
Reporter: GFP
Direct Detection
Results
Specimen 4b: postnatal adult; Lgr5tm1(cre/ERT2)Cle/Lgr5+ (more )
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 4b Expression is restricted to the 6-8 slender cells sandwiched between the Paneth cells at the crypt base; these are referred to as cycling crypt base columnar (CBC) cells.

Specimen 4c: postnatal adult; Lgr5tm1(cre/ERT2)Cle/Lgr5+ (more )
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 4c Expression is restricted to the 6-8 slender cells sandwiched between the Paneth cells at the crypt base; these are referred to as cycling crypt base columnar (CBC) cells.

Specimen 4e: postnatal adult; Lgr5tm1(cre/ERT2)Cle/Lgr5+ (more )
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 4e Expression is restricted to the 6-8 slender cells sandwiched between the Paneth cells at the crypt base; these are referred to as cycling crypt base columnar (CBC) cells.

Specimen 4f: postnatal adult; Lgr5tm1(cre/ERT2)Cle/Lgr5+ (more )
Structure Level Pattern Image Note
TS28: large intestine crypt of lieberkuhn Present Regionally restricted 4f Expression is restricted to a few cells located at the crypt base of colon.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory