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Tg(Cxcl9-RFP,Cxcl10-BFP)1Adl
Transgene Detail
Summary
Symbol: Tg(Cxcl9-RFP,Cxcl10-BFP)1Adl
Name: transgene insertion 1, Andrew D Luster
MGI ID: MGI:7509700
Synonyms: Reporting the Expression of CXCR3 ligands Tg, REX3 Tg
Transgene: Tg(Cxcl9-RFP,Cxcl10-BFP)1Adl  Location: unknown  
Alliance: Tg(Cxcl9-RFP,Cxcl10-BFP)1Adl page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA BAC clone containing the Cxcl9 and Cxcl10 genes was altered by the insertion of a RFP and BFP gene into the ATG start site of the Cxcl9 and Cxcl10 genes, respectively. Transgenic mice carrying the construct express the spectrally distinct fluorescent reporter proteins which report the expression of the CXCR3 ligands. (J:191089)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:191089 Groom JR, et al., CXCR3 Chemokine Receptor-Ligand Interactions in the Lymph Node Optimize CD4(+) T Helper 1 Cell Differentiation. Immunity. 2012 Dec 14;37(6):1091-103
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory