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Gene Expression Data
Assay Details
Assay
Reference: J:256987 Shi B, et al., MORC2B is essential for meiotic progression and fertility. PLoS Genet. 2018 Jan;14(1):e1007175
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7509253
Gene symbol: Dmc1
Gene name: DNA meiotic recombinase 1
Antibody: anti-Dmc1 (H-100; sc-22768)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 6D DMC1 +/-: postnatal day 18; Morc2btm1Jw/Morc2b+ (more )
Note: Double labeled: green - Dmc1; red - Sycp2 (assay MGI:7509245).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6D +/- DMC1 , 6D +/- merged
Specimen 6D DMC1 -/-: postnatal day 18; Morc2btm1Jw/Morc2btm1Jw (more )
Note: Double labeled: green - Dmc1; red - Sycp2 (assay MGI:7509245).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6D -/- DMC1 , 6D -/- merged Number of DMC1-positive foci decreased significatnly compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory