Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:212415
Kinzel B, et al., Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90
|
Assay type:
|
Immunohistochemistry
|
MGI Accession ID:
|
MGI:7509222
|
Gene symbol:
|
Mki67
|
Gene name:
|
antigen identified by monoclonal antibody Ki 67
|
Antibody:
|
anti-Ki67 (TEC-3; M7249)
|
Detection system:
|
Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
|
|
Results
|
Specimen
2C wt:
embryonic day 16.5
(more )
Specimen
2C wt:
(close )
Genetic Background:
|
involves: C57BL/6
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Specimen
2C Lgr5KO:
(close )
Specimen
2C Lgr4KO:
(close )
Specimen
2C Lgr4/5dKO:
(close )
Specimen
4F wt:
embryonic day 16.5
(more )
Specimen
4F wt:
(close )
Genetic Background:
|
involves: C57BL/6
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Specimen
4F Lgr5KO:
(close )
Specimen
4F Lgr4KO:
(close )
Specimen
4F Lgr4/5dKO:
(close )
Specimen
5D wt:
embryonic day 16.5
(more )
Specimen
5D wt:
(close )
Genetic Background:
|
involves: C57BL/6
|
Age:
|
embryonic day 16.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Formalin
|
Embedding:
|
Paraffin
|
Specimen
5D Lgr5KO:
(close )
Specimen
5D Lgr4KO:
(close )
Specimen
5D Lgr4/5dKO:
(close )
Structure |
Level |
Pattern |
Image |
Note |
TS24: metanephros |
Present |
|
5D Lgr4/5dKO
|
In this mutant there is a significant reduction in positive cells compared to wild-type.
|
|