Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:80146
Huang D, et al., Expression patterns of aquaporins in the inner ear: evidence for concerted actions of multiple types of aquaporins to facilitate water transport in the cochlea. Hear Res. 2002 Mar;165(1-2):85-95
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:7506314
|
|
Gene symbol:
|
Aqp1
|
|
Gene name:
|
aquaporin 1
|
|
|
Results
|
Specimen
10A:
postnatal adult
(more  )
Specimen
10A:
(close  )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: spiral ligament |
type 3 otic fibrocyte |
Strong |
Regionally restricted |
10A
|
Strong immunoreactivity was seen in a subset of fibrocytes in the spiral ligament mostly near the border with the bony shell of the cochlea. A thread-like staining pattern suggested that staining was localized on the cell processes.
|
| TS28: middle ear epithelium |
epithelial cell |
Present |
Regionally restricted |
10A
|
Expression was detected in the middle ear epithelial cells covering the promontory on the surface of bony shell.
|
Specimen
10B:
postnatal adult
(more )
Specimen
10B:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: perilymphatic channel |
Present |
Regionally restricted |
10B
|
Expression was detected in perilymphatic bone lining cells.
|
| TS28: capillary |
Present |
Regionally restricted |
10B
|
Expression was detected in capillary wall under the spiral ligament.
|
Specimen
11A:
postnatal adult
(more )
Specimen
11A:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: saccule |
Strong |
Regionally restricted |
11A
,
11B
|
Strong immunoreactivity was observed in the endolymphatic side of the saccular membrane.
|
| TS28: utricle |
Weak |
Regionally restricted |
11A
|
Very weak staining was detected in the utricle membrane.
|
Specimen
11C:
postnatal adult
(more )
Specimen
11C:
(close )
|
Genetic Background:
|
CD-1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: endolymphatic sac |
otic fibrocyte |
Strong |
Regionally restricted |
11C
|
Strong immunoreactivity was observed in fibrocytes of sub-epithelial connective tissue at the juncture between the rugose and smooth portions of the endolymphatic sac.
|
|
Analysis Tools