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Tg(Cyp1a1-ALPP)1Mktm
Transgene Detail
Summary
Symbol: Tg(Cyp1a1-ALPP)1Mktm
Name: transgene insertion 1, Masanori Kitamura
MGI ID: MGI:7506292
Synonyms: Tg(DRE-SEAP)
Transgene: Tg(Cyp1a1-ALPP)1Mktm  Location: unknown  
Alliance: Tg(Cyp1a1-ALPP)1Mktm page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Cyp1a1-ALPP)1Mktm expresses 1 gene
 
Tg(Cyp1a1-ALPP)1Mktm expression driven by 1 gene
 
Mutation detailsMMTV-DRE promoter [1.8 kb regulatory fragment consists of the following two parts: (1)a 484-bp fragment from the upstream region of the mouse Cyp1A1 gene that contains 4 dioxin responsive elements (DRE), and (2) a 1330-bp fragment from a part of the mouse mammary tumor virus (MMTV) promoter lacking in glucocorticoid responsive enhancers] driving inducible expression of human secreted alkaline phoaphatase cDNA with an SV40 Late mRNA poly A. (J:337738)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:337738 Hiramatsu N, et al., Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP: evidence for systemic, transient ER stress during endotoxemia. Nucleic Acids Re. 2006;34(13):e93
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory