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Gene Expression Data
Assay Details
Assay
Reference: J:282806 Chen NY, et al., An absence of lamin B1 in migrating neurons causes nuclear membrane ruptures and cell death. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25870-25879
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7506221
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase-3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1A Control: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cortical plate Ambiguous 1A Control (merged) , 1A Control Caspase3 Expression in control not described.
Specimen 1A Lmnb1 KO: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+, Lmnb1tm1.1Sgy/Lmnb1tm1.1Sgy (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cortical plate Present 1A Lmnb1 KO Caspase3 , 1A Lmnb1 KO (merged) Substantial expression in cortical plate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory