Tg(tetO-CAT-Pdx1)1Miya
Transgene Detail
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| Symbol: |
Tg(tetO-CAT-Pdx1)1Miya |
| Name: |
transgene insertion 1, Jun-ichi Miyazaki |
| MGI ID: |
MGI:7505583 |
| Synonyms: |
CAG-CAT-PDX1 |
| Transgene: |
Tg(tetO-CAT-Pdx1)1Miya Location: unknown
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| Alliance: |
Tg(tetO-CAT-Pdx1)1Miya page
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| Transgene Type: |
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Transgenic (Conditional ready, Epitope tag, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(tetO-CAT-Pdx1)1Miya expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Pdx1 (MGI:102851) |
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Tg(tetO-CAT-Pdx1)1Miya expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: This Cre recombinase reporter transgene employs the "CAG promoter," which consists of the cytomegalovirus immediate early (CMV-EI) enhancer followed by a 1.3-kb DNA segment including the promoter, first exon and first intron of the chicken beta-actin gene, with the 3' splice junction sequence replaced by that of the rabbit hemoglobin beta gene. The promoter is separated from the PDX1 coding sequence and FLAG epitope tag, with a rabbit globin polyadenylation signal, by a loxP-flanked chloramphenicol acetyltransferase (cat) gene with the SV40 small t intron and polyadenylation signal.
(J:127214)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:127214 Miyatsuka T, et al., Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis. Biochem Biophys Res Commun. 2003 Oct 24;310(3):1017-25 |
| All: |
9 reference(s) |
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Analysis Tools
