Gene Expression Data
Assay Details
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Assay
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Reference:
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J:320312
Pitolli C, et al., Characterization of TG2 and TG1-TG2 double knock-out mouse epidermis. Amino Acids. 2017 Mar;49(3):635-642
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7505545
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Gene symbol:
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Ivl
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Gene name:
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involucrin
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Antibody:
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anti-Involucrin
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Detection system:
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Secondary antibody coupled to Alexa Fluor 488
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Results
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Specimen
2 WT:
embryonic day 18.5
(more  )
Specimen
2 WT:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2 TG1KO:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Tgm1tm1Kfyn/Tgm1tm1Kfyn
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: epidermis granular layer |
Present |
Regionally restricted |
2_Involucrin TG1KO
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In this mutant expression and distribution was dispersed compared to wild-type.
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| TS26: epidermis cornified layer |
Present |
Regionally restricted |
2_Involucrin TG1KO
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Expression in this mutant showed that proteins were not correctly incorporated compared to wild-type.
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Specimen
2 TG2KO:
(close )
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Genetic Background:
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involves: C57BL/6
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Mutant Allele(s):
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Tgm2tm1Gml/Tgm2tm1Gml
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2 TG1-TG2DKO:
(close )
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Genetic Background:
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involves: 129S1/SvImJ * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Tgm1tm1Kfyn/Tgm1tm1Kfyn
Tgm2tm1Gml/Tgm2tm1Gml
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: epidermis granular layer |
Present |
Regionally restricted |
2_Involucrin TG1-TG2DKO
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In this mutant expression and distribution was dispersed compared to wild-type.
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| TS26: epidermis cornified layer |
Present |
Regionally restricted |
2_Involucrin TG1-TG2DKO
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Expression in this mutant showed that proteins were not correctly incorporated compared to wild-type.
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Analysis Tools