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Gene Expression Data
Assay Details
Assay
Reference: J:221782 Pai YJ, et al., Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice. Nat Commun. 2015;6:6388
Assay type: RNA in situ
MGI Accession ID: MGI:7496099
Gene symbol: Gldc
Gene name: glycine decarboxylase
Probe: Gldc cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4a top: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS14: caudal neuropore Strong 4a top
TS14: neural fold Strong 4a top
TS14: neural tube Strong 4a top
Specimen 4a bottom: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS14: caudal neuropore Strong 4a bottom
TS14: neural fold Strong 4a bottom
TS14: neural tube Strong 4a bottom
Specimen 4b: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Strong 4b
TS15: neural tube Strong 4b Intense expression was detected throughout the closed neural tube.
Specimen 4c: embryonic day 8.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS14: neural fold Strong 4c
Specimen 4d: embryonic day 9.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS15: neural tube Strong 4d Intense expression was detected throughout the closed neural tube.
Specimen S1A top: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS14: caudal neuropore Strong S1A top
TS14: neural fold Strong S1A top
TS14: neural tube Strong S1A top
Specimen S1A bottom: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS14: caudal neuropore Strong S1A bottom
TS14: neural fold Strong S1A bottom
TS14: neural tube Strong S1A bottom
Specimen S1B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Strong S1B
TS15: neural tube Strong S1B Expression persisted in the closed neural tube.
TS15: limb Present S1B
Specimen S1C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Strong S1C Expression persisted in the closed neural tube.
TS17: limb Present S1C
Specimen S1D: embryonic day 8.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS14: neural fold Strong S1D
Specimen S1E: embryonic day 8.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS14: neural fold Strong S1E
TS14: foregut diverticulum Present S1E
Specimen S1F: embryonic day 8.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS14: neural tube Strong S1F
TS14: foregut diverticulum Present S1F
Specimen S1G: embryonic day 8.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS14: caudal neuropore Present S1G
Specimen S1H: embryonic day 9.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS15: neural tube Strong S1H Expression persisted in the closed neural tube.
Specimen S1I: embryonic day 9.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS15: neural tube Strong S1I Expression persisted in the closed neural tube.
TS15: limb Present S1I
Specimen S1J: embryonic day 10.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS17: neural tube Strong S1J Expression persisted in the closed neural tube.
Specimen S1K: embryonic day 10.5 (more )
Note: Fix: 0.2% glutaraldehyde; 4% paraformaldehyde.
Structure Level Pattern Image Note
TS17: neural tube Strong S1K Expression persisted in the closed neural tube.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory