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Gene Expression Data
Assay Details
Assay
Reference: J:221782 Pai YJ, et al., Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice. Nat Commun. 2015;6:6388
Assay type: RT-PCR
MGI Accession ID: MGI:7496089
Gene symbol: Gldc
Gene name: glycine decarboxylase
Probe: Gldc-pF, Gldc-pR
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Gapdh.
Results
Image: 1d ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
+/+ P w 5 TS28: liver Present Not Specified; total RNA Not Specified Not Specified
GT1/+ P w 5 TS28: liver Present (a) Not Specified; total RNA B6.129P2-GldcGt(EUCG0001d02)Hmgu GldcGt(EUCG0001d02)Hmgu/Gldc+Not Specified
GT1/GT1 P w 5 TS28: liver Weak (b) Not Specified; total RNA B6.129P2-GldcGt(EUCG0001d02)Hmgu GldcGt(EUCG0001d02)Hmgu/GldcGt(EUCG0001d02)HmguNot Specified
+/+ P w 5 TS28: brain Present Not Specified; total RNA Not Specified Not Specified
GT1/+ P w 5 TS28: brain Present (a) Not Specified; total RNA B6.129P2-GldcGt(EUCG0001d02)Hmgu GldcGt(EUCG0001d02)Hmgu/Gldc+Not Specified
GT1/GT1 P w 5 TS28: brain Weak (b) Not Specified; total RNA B6.129P2-GldcGt(EUCG0001d02)Hmgu GldcGt(EUCG0001d02)Hmgu/GldcGt(EUCG0001d02)HmguNot Specified
Notes:
(a) Expression was reduced 50-60% in heterozygotes.
(b) Expression was reduced 95% in homozygotes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory