Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tbx2em1(cre/ESR1*)Zyliu
Name:	T-box 2; endonuclease-mediated mutation 1, Zhiyong Liu
MGI ID:	MGI:7495797
Synonyms:	Tbx2*3XHA-P2A-iCreER-T2A-EGFP, Tbx2-HA
Gene:	Tbx2  Location: Chr11:85723441-85732774 bp, + strand  Genetic Position: Chr11, 51.34 cM
Alliance:	Tbx2em1(cre/ESR1*)Zyliu page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Epitope tag, Inducible, Recombinase, Reporter) Mutation:    Insertion   Tbx2em1(cre/ESR1*)Zyliu expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tbx2 (MGI:98494)   Mutation details: CRISPR/cas9 genome editing is used to insert a 3Xhemagluttin tag (HA), a P2A self-cleaving peptide sequence, an cre/ERT2, a T2A site, followed by an EGFP reporter close to the TGA stop codon in exon 7. (J:337553)

Activity:	Tissue activity of this recombinase allele
Driver:	Tbx2 (mouse) Summary of all recombinase alleles driven by Tbx2. Alliance mouse Tbx2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx2 Mutation:	27 strains or lines available

Original:	J:337553 Bi Z, et al., Development and transdifferentiation into inner hair cells require Tbx2. Natl Sci Rev. 2022 Dec;9(12):nwac156
All:	1 reference(s)