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Tg(GPX4)6Vrmn
Transgene Detail
Summary
Symbol: Tg(GPX4)6Vrmn
Name: transgene insertion 6, Holly Van Remmen
MGI ID: MGI:7494189
Synonyms: Tg(GPX4)
Transgene: Tg(GPX4)6Vrmn  Location: unknown  
Alliance: Tg(GPX4)6Vrmn page
Transgene
origin
Strain of Origin:  B6D2F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(GPX4)6Vrmn expresses 1 gene
 
Tg(GPX4)6Vrmn expression driven by 1 gene
 
Mutation detailsA human P1 clone, containing the intact human GPX4 gene (about 3 kb) plus about 30 and 20 kb of 5'- and 3'-flanking sequence, respectively, was used to generate transgenic mice. (J:94555)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:94555 Ran Q, et al., Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis. J Biol Chem. 2004 Dec 31;279(53):55137-46
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory