Tg(SFTPC-SFTPA2*)T4Jflo
Transgene Detail
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| Symbol: |
Tg(SFTPC-SFTPA2*)T4Jflo |
| Name: |
transgene insertion T4, Joanna Floros |
| MGI ID: |
MGI:7493599 |
| Synonyms: |
hTG SP-A2(1A3) |
| Transgene: |
Tg(SFTPC-SFTPA2*)T4Jflo Location: unknown Genetic Position: ChrUN, Syntenic
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| Alliance: |
Tg(SFTPC-SFTPA2*)T4Jflo page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(SFTPC-SFTPA2*)T4Jflo expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
SFTPA2 (729238) |
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variant 1A3 coding sequence |
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Mutation details: The transgenic construct contains the 3.7 kb human SFTPC (surfactant associated protein C) promoter, the 1.3 kb human SFTPA2 (surfactant associated protein A2) variant 1A3 coding sequence containing the 5' and 3' UTR and the entire coding region followed by an SV40 polyA signal. Founder line T4 has medium to high expression.
(J:161087)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:161087 Wang G, et al., Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products. J Biol Chem. 2010 Apr 16;285(16):11998-2010 |
| All: |
1 reference(s) |
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Analysis Tools
