Trpv6 RT-PCR Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:203695 Lieben L, et al., Maternal hypervitaminosis D reduces fetal bone mass and mineral acquisition and leads to neonatal lethality. Bone. 2013 Nov;57(1):123-31
Assay type:	RT-PCR
MGI Accession ID:	MGI:7492495
Gene symbol:	Trpv6
Gene name:	transient receptor potential cation channel, subfamily V, member 6

Probe:	Trpv6-pF, Trpv6-pR
Assay notes:	Quantitative RT-PCR. Relative expression was normalized to Hprt1.

Results

Image: 2B

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Amount	Genetic Background	Mutant Allele(s)	Sex	Note
+/+	E18.5	TS26: extraembryonic component TS28: placenta	Present	Not Specified; total RNA	involves: 129S1/Sv * 129X1/SvJ		Not Specified	Mother was Vdr+/+.
-/-	E18.5	TS26: extraembryonic component TS28: placenta	Present (a)	Not Specified; total RNA	involves: 129S1/Sv * 129X1/SvJ	Vdr^tm1.1Gcm/Vdr^tm1.1Gcm	Not Specified	Mother was Vdr-/-.
+/-	E18.5	TS26: extraembryonic component TS28: placenta	Present (b)	Not Specified; total RNA	involves: 129S1/Sv * 129X1/SvJ	Vdr^tm1.1Gcm/Vdr⁺	Not Specified	Mother was Vdr-/-.

Notes:
(a) There was a significant reduction in expression in this mutant compared to offspring from wild-type mothers.
(b) There was a significant further reduction in expression in this mutant compared to Vdr-/- littermates offspring from Vdr-/- mothers.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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