About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:218695 Soggia A, et al., von Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-alpha and VEGF-A upregulation. Diabetologia. 2014 Nov;57(11):2348-56
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7492352
Gene symbol: Ins1
Gene name: insulin I
Antibody: anti-insulin
Results
Specimen 4a Control: embryonic day 17.5; Vhltm1Jae/Vhltm1Jae (more )
Structure Cell Type Level Pattern Image Note
TS25: pancreas type B pancreatic cell Present Clusters 4a Control Expression in large clusters of beta cells.
Specimen 4a Sox9-Cre: embryonic day 17.5; Sox9tm3(cre)Crm/Sox9+, Vhltm1Jae/Vhltm1Jae (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS25: pancreas type B pancreatic cell Trace Scattered 4a Sox9-Cre Expression only in a few scattered cells.
Specimen S7 Insulin Control: embryonic day 17.5; Vhltm1Jae/Vhltm1Jae (more )
Note: Double labeled: red - Ins1 and Ins2; green - Amy (assay MGI:7492357).
Structure Level Pattern Image Note
TS25: pancreas Present S7_Insulin/Amylase Control
Specimen S7 Insulin Sox9-Cre: embryonic day 17.5; Sox9tm3(cre)Crm/Sox9+, Vhltm1Jae/Vhltm1Jae (more )
Note: Conditional mutant. Double labeled: red - Ins1 and Ins2; green - Amy (assay MGI:7492357).
Structure Level Pattern Image Note
TS25: pancreas Present S7_Insulin/Amylase Sox9-Cre
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory