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Gene Expression Data
Assay Details
Assay
Reference: J:186285 Lefkovics K, et al., Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405
Assay type: RNA in situ
MGI Accession ID: MGI:7492297
Gene symbol: Cdh12
Gene name: cadherin 12
Probe: Cdh12 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Using another probe (MGI:6169470) based on the Allen Brain Atlas probe information showed identical expression pattern.
Results
Specimen 3H: postnatal adult (more )
Structure Level Pattern Image Note
TS28: somatosensory cortex Present 3H

Specimen 5A: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: hippocampus Absent 5A Summarized in Table 3.

Specimen 5B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 5B Expressed in the hippocampal plate (the future pyramidal cell layer). High expression in the marginal zone. Summarized in Table 3.

Specimen 5C: postnatal day 1 (more )
Structure Cell Type Level Pattern Image Note
TS27: hippocampus CA3 hippocampal pyramidal neuron Strong 5C
TS27: CA1 pyramidal cell layer Weak 5C
TS27: hippocampus molecular layer Present 5C Summarized in Table 3.
TS27: hippocampus stratum lacunosum Present 5C Summarized in Table 3.

Specimen 7A1: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: hippocampus stratum oriens Present Single cells 7A1 Expressed only in a few cells.
TS28: CA1 pyramidal cell layer Strong 7A1
TS28: hippocampus stratum radiatum Trace 7A1
TS28: hippocampus molecular layer Ambiguous 7A1
TS28: hippocampus stratum lacunosum Ambiguous 7A1

Specimen 7A2: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus stratum oriens Present Single cells 7A2 Expressed only in a few cells.
TS28: CA1 pyramidal cell layer Strong 7A2
TS28: hippocampus stratum radiatum Present 7A2
TS28: hippocampus molecular layer Absent 7A2
TS28: hippocampus stratum lacunosum Absent 7A2

Specimen 7A3: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: CA3 pyramidal cell layer Strong 7A3
TS28: hippocampus stratum lucidum Present 7A3

Specimen 7A4: postnatal adult (more )
Structure Level Pattern Image Note
TS28: CA3 pyramidal cell layer Strong 7A4
TS28: hippocampus stratum lucidum Present 7A4

Specimen 7A5: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Weak 7A5
TS28: dentate gyrus hilus Present 7A5

Specimen 7A6: postnatal adult (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present 7A6 Significantly increased expression.
TS28: dentate gyrus hilus Present 7A6

Specimen 8G: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: hippocampus stratum radiatum Trace 8G

Specimen 10A1: embryonic day 14.0 (more )
Note: Summarized in Fig. 11.
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Absent 10A1
TS22: cerebral cortex subventricular zone Absent 10A1
TS22: cerebral cortex ventricular layer Absent 10A1
TS22: cortical plate Absent 10A1
TS22: cortical subplate Absent 10A1
TS22: cerebral cortex marginal layer Present 10A1

Specimen 10A2: embryonic day 16.0 (more )
Note: Summarized in Fig. 11.
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Absent 10A2
TS24: cerebral cortex marginal layer Absent 10A2
TS24: cerebral cortex subventricular zone Absent 10A2
TS24: cerebral cortex ventricular layer Absent 10A2
TS24: cortical subplate Absent 10A2
TS24: cortical plate Present 10A2

Specimen 10A3: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular layer Absent 10A3

Specimen 10A4: postnatal day 1 (more )
Note: Summarized in Fig. 11.
Structure Level Pattern Image Note
TS27: cerebral cortex intermediate zone Absent 10A4
TS27: cortical layer I Absent 10A4
TS27: cortical layer IV Absent 10A4
TS27: cortical subplate Absent 10A4
TS27: cortical layer II Present 10A4
TS27: cortical layer III Present 10A4
TS27: cortical layer V Present 10A4
TS27: cortical layer VI Present 10A4

Specimen 10A5: postnatal day 10 (more )
Note: Summarized in Fig. 11.
Structure Level Pattern Image Note
TS28: cerebral hemisphere white matter Absent 10A5
TS28: cortical layer I Absent 10A5
TS28: cortical layer IV Absent 10A5
TS28: cortical subplate Absent 10A5
TS28: cortical layer II Present 10A5
TS28: cortical layer III Present 10A5
TS28: cortical layer V Present 10A5
TS28: cortical layer VI Present 10A5

Specimen 10A6: postnatal adult (more )
Note: Summarized in Fig. 11.
Structure Level Pattern Image Note
TS28: cerebral hemisphere white matter Absent 10A6
TS28: cortical layer I Absent 10A6
TS28: cortical subplate Absent 10A6
TS28: cortical layer II Present 10A6
TS28: cortical layer III Present 10A6
TS28: cortical layer IV Present 10A6
TS28: cortical layer V Present 10A6
TS28: cortical layer VI Present 10A6


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory