Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Bsx-icre)1Kess
Name:	transgene insertion 1, Nicoletta Kessaris
MGI ID:	MGI:7490135
Synonyms:	Bsx-Cre
Transgene:	Tg(Bsx-icre)1Kess  Location: unknown
Alliance:	Tg(Bsx-icre)1Kess page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Bsx-icre)1Kess expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Bsx (MGI:2669849)   Mutation details: Homologous recombination in bacteria was used to modify a 180 Kb BAC RP24-255N16 containing 70 Kb upstream and 110 Kb downstream of the Bsx gene. The codon-improved Cre recombinase (iCre) conntaining a nuclear localization signal was fused to the initiation codon of the genes using a PCR-based approach. This was followed by a Simian Virus 40 polyadenylation signal and a Kanamycin resistance cassette that was flanked by FRT sites for the selection of recombinant BACs. BAC recombination was designed to delete the remaining ATG-encoding exon together with 50-200 bp from the downstream intron. Mice were generated by pronuclear injection of the construct into fertilized oocytes. No line number is given. (J:330767)

Activity:	Tissue activity of this recombinase allele
Driver:	Bsx (mouse) Summary of all recombinase alleles driven by Bsx. Comparative matrix view of recombinase activities Alliance mouse Bsx gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:330767 Magno L, et al., Fate mapping reveals mixed embryonic origin and unique developmental codes of mouse forebrain septal neurons. Commun Biol. 2022 Oct 27;5(1):1137
All:	1 reference(s)