Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Pou4f1tm1(flpo/ERT2)Past
Name:	POU domain, class 4, transcription factor 1; targeted mutation 1, Jeroen Pasterkamp
MGI ID:	MGI:7489615
Synonyms:	Brn3a-mTurquoiseHIS-FlpOERT2
Gene:	Pou4f1  Location: Chr14:104699112-104705435 bp, - strand  Genetic Position: Chr14, 54.21 cM, cytoband E1-E3
Alliance:	Pou4f1tm1(flpo/ERT2)Past page

Germline Transmission:	Earliest citation of germline transmission: J:326542
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Pou4f1tm1(flpo/ERT2)Past expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Pou4f1 (MGI:102525)   Mutation details: The targeting vector consists of a T2A-mTurquoiseHIS-P2A-FlpO fragment inserted upstream of a lox511-Neo-lox511 cassette was targeted into the Pou4f1 (Brn3a) gene by homologous recombination in ES cells. (J:326542)

Activity:	Tissue activity of this recombinase allele
Driver:	Pou4f1 (mouse) Summary of all recombinase alleles driven by Pou4f1. Comparative matrix view of recombinase activities Alliance mouse Pou4f1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou4f1 Mutation:	13 strains or lines available

Original:	J:326542 van de Haar LL, et al., Molecular signatures and cellular diversity during mouse habenula development. Cell Rep. 2022 Jul 5;40(1):111029
All:	1 reference(s)