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Gene Expression Data
Assay Details
Assay
Reference: J:79280 Kido Y, et al., Effects of Mutations in the Insulin-like Growth Factor Signaling System on Embryonic Pancreas Development and beta -Cell Compensation to Insulin Resistance. J Biol Chem. 2002 Sep 27;277(39):36740-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7489526
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-glucagon
Assay notes: These data are shown in a table and described in the text.
Results
Specimen WT E18.5: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: islets of Langerhans pancreatic A cell Present
Specimen Insr-/-: embryonic day 18.5; Insrtm1Dac/Insrtm1Dac (more )
Structure Cell Type Level Pattern Image Note
TS26: islets of Langerhans pancreatic A cell Present
Specimen Igf1r-/-: embryonic day 18.5; Igf1rtm1Arge/Igf1rtm1Arge (more )
Structure Cell Type Level Pattern Image Note
TS26: islets of Langerhans pancreatic A cell Present
Specimen Insr-/-;Igf1r-/-: embryonic day 18.5; Igf1rtm1Arge/Igf1rtm1Arge, Insrtm1Dac/Insrtm1Dac (more )
Structure Cell Type Level Pattern Image Note
TS26: islets of Langerhans pancreatic A cell Present In this mutant the relative alpha-cell area was increased about 3-fold, as a result of the decreased area of exocrine pancreas compared to wild-type.
Specimen WT P: postnatal (more )
Structure Level Pattern Image Note
TS28: islets of Langerhans Present
Specimen ir+/-: postnatal; Insrtm1Dac/Insr+ (more )
Structure Level Pattern Image Note
TS28: islets of Langerhans Present In this mutant the islets were moderately enlarged and unevenly distributed compared to wild-type.
Specimen igf1r+/-: postnatal; Igf1rtm1Arge/Igf1r+ (more )
Structure Level Pattern Image Note
TS28: islets of Langerhans Present
Specimen ir+/-;igf1r+/-: postnatal; Igf1rtm1Arge/Igf1r+, Insrtm1Dac/Insr+ (more )
Structure Level Pattern Image Note
TS28: islets of Langerhans Present In this mutant the islets were moderately enlarged and unevenly distributed compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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