Tg(CAG-AKT1/ERT2,-EGFP)1Nkn
Transgene Detail
|
|
| Symbol: |
Tg(CAG-AKT1/ERT2,-EGFP)1Nkn |
| Name: |
transgene insertion 1, Toru Nakano |
| MGI ID: |
MGI:7488668 |
| Synonyms: |
AKT-MER, Tg(AKT/Ert2,EGFP)1Nkn, Tg(CAG-AKT1/ERT2,EGFP)1Nkn |
| Transgene: |
Tg(CAG-AKT1/ERT2,-EGFP)1Nkn Location: unknown
|
| Alliance: |
Tg(CAG-AKT1/ERT2,-EGFP)1Nkn page
|
|
| Strain of Origin: |
C57BL/6 x DBA
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence, Reporter) |
| Mutation: |
|
Insertion
|
| |
|
Tg(CAG-AKT1/ERT2,-EGFP)1Nkn expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Akt1 (MGI:87986) |
|
|
| |
|
Mutation details: This transgene express a fusion protein composed of a myristoylated constitutively active form of human Akt and the ligand-binding domain of a mutant estrogen receptor under the control of the CAG promoter. The Akt-Mer was also fused to IRES-EGFP, can be monitored Akt-Mer expression by GFP fluorescence.
(J:125544)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:125544 Murayama K, et al., Akt activation induces epidermal hyperplasia and proliferation of epidermal progenitors. Oncogene. 2007 Jul 19;26(33):4882-8 |
| All: |
5 reference(s) |
|
Analysis Tools
