Gene Expression Data
Assay Details
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Assay
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Reference:
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J:239434
Fleger-Weckmann A, et al., Deletion of the epidermis derived laminin gamma1 chain leads to defects in the regulation of late hair morphogenesis. Matrix Biol. 2016 Dec;56:42-56
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7488636
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Gene symbol:
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Foxn1
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Gene name:
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forkhead box N1
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Antibody:
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anti-FoxN1
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Detection system:
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Secondary antibody coupled to Alexa Fluor 568
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Results
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Specimen
5b P6 control:
postnatal day 6; Lamc1tm1Strl/?
(more  )
Specimen
5b P6 control:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Lamc1tm1Strl/?
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hair follicle |
Present |
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5b FoxN1 P6 control inset
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5b FoxN1 P6 control
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Specimen
5b P6 EKO:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Lamc1tm1Strl/Lamc1tm1Strl
Tg(KRT14-cre)1Cgn/0
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hair inner root sheath |
Weak |
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5b FoxN1 P6 EKO
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5b FoxN1 P6 EKO inset
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Reduced expression in hair shalf and inner root sheath compared to control
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| TS28: hair shaft |
Weak |
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5b FoxN1 P6 EKO
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5b FoxN1 P6 EKO inset
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Reduced expression in hair shalf and inner root sheath compared to control
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Specimen
5b P10 control:
postnatal day 10; Lamc1tm1Strl/?
(more )
Specimen
5b P10 control:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Lamc1tm1Strl/?
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hair follicle |
Present |
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5b FoxN1 P10 control
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5b FoxN1 P10 control inset
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Specimen
5b P10 EKO:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Lamc1tm1Strl/Lamc1tm1Strl
Tg(KRT14-cre)1Cgn/0
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hair inner root sheath |
Weak |
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5b FoxN1 P10 EKO inset
,
5b FoxN1 P10 EKO
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Reduced expression in hair shalf and inner root sheath compared to control
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| TS28: hair shaft |
Weak |
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5b FoxN1 P10 EKO inset
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5b FoxN1 P10 EKO
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Reduced expression in hair shalf and inner root sheath compared to control
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Analysis Tools