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Gene Expression Data
Assay Details
Assay
Reference: J:68331 Kim K, et al., Polycystin 1 is required for the structural integrity of blood vessels. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1731-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7488443
Gene symbol: Pkd1
Gene name: polycystin 1, transient receptor potential channel interacting
Antibody: anti-LRR
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4A: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: hindlimb Present 4A Expressed in capillary and small vessels.
TS22: blood vessel endothelium blood vessel endothelial cell Present 4A Expressed in capillary and small vessels in the hindlimb.
TS22: blood vessel smooth muscle blood vessel smooth muscle cell Present 4A Expressed in capillary and small vessels in the hindlimb.

Specimen 4B: embryonic day 14.5; Pkd1tm1Maa/Pkd1tm1Maa (more )
Structure Cell Type Level Pattern Image Note
TS22: hindlimb Present 4B Expressed in capillary and small vessels, similar as in the wild-type.
TS22: blood vessel endothelium blood vessel endothelial cell Present 4B Expressed in capillary and small vessels in the hindlimb, similar as in the wild-type.
TS22: blood vessel smooth muscle blood vessel smooth muscle cell Present 4B Expressed in capillary and small vessels in the hindlimb, similar as in the wild-type.

Specimen 4C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal tubule Present 4C Expressed on the apical surfaces.
TS22: nephron Present 4C

Specimen 4E: embryonic day 14.5; Pkd1tm1Maa/Pkd1tm1Maa (more )
Structure Level Pattern Image Note
TS22: renal tubule Present 4E Expressed on the apical surfaces, similar as in the wild-type.
TS22: nephron Present 4E

Specimen not shown: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: blood vessel blood vessel endothelial cell Present Regionally restricted It was not detected in endothelium of major vessels.
TS22: gut Present
TS22: skeletal muscle Present
TS22: pancreatic duct endothelial cell Present

Specimen not shown: embryonic day 14.5; Pkd1tm1Maa/Pkd1tm1Maa (more )
Structure Cell Type Level Pattern Image Note
TS22: blood vessel blood vessel endothelial cell Present Regionally restricted It was not detected in endothelium of major vessels.
TS22: gut Present
TS22: skeletal muscle Present
TS22: pancreatic duct endothelial cell Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory