About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:167305 Sims-Lucas S, et al., Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development. Dev Dyn. 2011 Jan;240(1):240-9
Assay type: RNA in situ
MGI Accession ID: MGI:7488182
Gene symbol: Gdnf
Gene name: glial cell line derived neurotrophic factor
Probe: Gdnf probe
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: Controls were littermates.
Results
Specimen 8A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present Regionally restricted 8A Expression is adjacent to ureteric buds.
Specimen 8B: embryonic day 10.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm3.1Lni/Fgfr2tm3.1Lni, Tg(Pax3-cre)1Joe/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present 8B Expression in this mutant is similar to controls.
Specimen 8C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present Regionally restricted 8C Expression is surrounding the ureteric epithelia.
Specimen 8D: embryonic day 11.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm3.1Lni/Fgfr2tm3.1Lni, Tg(Pax3-cre)1Joe/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Absent 8D
Specimen 8E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present 8E
Specimen 8F: embryonic day 11.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm3.1Lni/Fgfr2tm3.1Lni, Tg(Pax3-cre)1Joe/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Absent 8F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/09/2025
MGI 6.24 		The Jackson Laboratory