About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:309377 Betterman KL, et al., Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow. J Clin Invest. 2020 Jun 1;130(6):3315-3328
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7486756
Gene symbol: Lama5
Gene name: laminin, alpha 5
Antibody: 4G6
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2H: embryonic day 18.5 (more )
Note: Double labeled: red - Lama5; green - Foxc2 (assay MGI:7486757).
Structure Level Pattern Image Note
TS26: lymphatic vessel Present Regionally restricted 2H Lama5 is a marker for lymphatic vessel valve maturation. Expression was detected in mesenteric lymphatic vessels at E18.5.

Specimen 2K: embryonic day 18.5; Fat4tm1Hmc/Fat4tm1Hmc, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant. Double labeled: red - Lama5; green - Foxc2 (assay MGI:7486757).
Structure Level Pattern Image Note
TS26: lymphatic vessel Present Regionally restricted 2K Less expression was detected in mesenteric lymphatic vessels in the mutant compared with control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory