Gene Expression Data
Assay Details
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Assay
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Reference:
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J:92057
Waclaw RR, et al., The homeobox gene Gsh2 is required for retinoid production in the embryonic mouse telencephalon. Development. 2004 Aug;131(16):4013-20
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7486584
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Gene symbol:
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Ppp1r1b
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Gene name:
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protein phosphatase 1, regulatory inhibitor subunit 1B
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Antibody:
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anti-DARPP-32
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
4E:
embryonic day 18.5
(more  )
Specimen
4E:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4F:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: corpus striatum |
Weak |
Regionally restricted |
4F
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Disproportionate reduction in number of expressing neurons compared to wild type and Pax6 single mutant.
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Specimen
4G:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Pax6Sey/Pax6Sey
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4H:
(close )
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Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Gsx2tm1Ssp/Gsx2tm1Ssp
Pax6Sey/Pax6Sey
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: corpus striatum |
Weak |
Regionally restricted |
4H
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Number of expressing neurons remains disproportionately reduced, similar to that of Gsh2 single mutant.
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Analysis Tools