Six1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:335760 Zhang T, et al., The role of Eya1 and Eya2 in the taste system of mice from embryonic stage to adulthood. Front Cell Dev Biol. 2023;11:1126968
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7486071
Gene symbol:	Six1
Gene name:	sine oculis-related homeobox 1

Antibody:	anti-SIX1 (D4A8K; #12891)
Detection system:	Secondary antibody

Results

2B CVP +/+ ©

Specimen 2B CVP +/+: embryonic day 18.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS26: circumvallate papillae		Present	Regionally restricted	2B CVP +/+	Expression in at top of CVP epithelium and in trenches.
TS26: von Ebner's gland		Present		2B CVP +/+
TS26: tongue muscle	tongue muscle cell	Present		2B CVP +/+

2B CVP -/- ©

Specimen 2B CVP -/-: embryonic day 18.5; Eya1^tm1Rilm/Eya1^tm1Rilm (more

)

Structure	Cell Type	Level	Image	Note
TS26: circumvallate papillae		Absent	2B CVP -/-	No expression in papilla and trench epithelium.
TS26: von Ebner's gland		Absent	2B CVP -/-
TS26: tongue muscle	tongue muscle cell	Present	2B CVP -/-

2B FOP +/+ ©

Specimen 2B FOP +/+: embryonic day 18.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS26: foliate papillae		Present	Regionally restricted	2B FOP +/+	Expression in FOP trenches.
TS26: von Ebner's gland		Present		2B FOP +/+
TS26: tongue muscle	tongue muscle cell	Present		2B FOP +/+

2B FOP -/- ©

Specimen 2B FOP -/-: embryonic day 18.5; Eya1^tm1Rilm/Eya1^tm1Rilm (more

)

Structure	Cell Type	Level	Image	Note
TS26: foliate papillae		Absent	2B FOP -/-	No expression in papilla and trench epithelium.
TS26: von Ebner's gland		Absent	2B FOP -/-
TS26: tongue muscle	tongue muscle cell	Present	2B FOP -/-

7C CVP +/+ ©

Specimen 7C CVP +/+: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: circumvallate papillae	Present		7C CVP +/+	Expression in trenches.

7C CVP -/- ©

Specimen 7C CVP -/-: embryonic day 18.5; Eya2^tm1Px/Eya2^tm1Px (more

)

Structure	Level	Pattern	Image	Note
TS26: circumvallate papillae	Present		7C CVP -/-	No significant difference compared to wild type.

7C FOP +/+ ©

Specimen 7C FOP +/+: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: foliate papillae	Present	Regionally restricted	7C FOP +/+	Expression in trenches.

7C FOP -/- ©

Specimen 7C FOP -/-: embryonic day 18.5; Eya2^tm1Px/Eya2^tm1Px (more

)

Structure	Level	Pattern	Image	Note
TS26: foliate papillae	Present		7C FOP -/-	No significant difference compared to wild type.

8E LacZ/+ ©

Specimen 8E Six1 LacZ/+: postnatal adult; Eya2^tm2Px/Eya2⁺ (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: taste bud	type II taste cell	Present		8E LacZ/+ , 8E LacZ/+ (Merge)	Expression in Type II taste receptors.

8E LacZ/LacZ ©

Specimen 8E Six1 LacZ/LacZ: postnatal adult; Eya2^tm2Px/Eya2^tm2Px (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: taste bud	type II taste cell	Present	Regionally restricted	8E LacZ/LacZ (Merge) , 8E LacZ/LacZ	Number of Type II taste receptors reduced compared to wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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