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Gene Expression Data
Assay Details
Assay
Reference: J:335760 Zhang T, et al., The role of Eya1 and Eya2 in the taste system of mice from embryonic stage to adulthood. Front Cell Dev Biol. 2023;11:1126968
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7486070
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-SOX2 (PA1-094)
Detection system: Secondary antibody
Results
Specimen 2A FUP +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: fungiform papillae Strong Regionally restricted 2A FUP +/+ Strong expression in well-developed taste bud with clustered cells.
TS26: tongue epithelium Present Regionally restricted 2A FUP +/+ Relatively weak expression in surounding epithelial cells.
Specimen 2A FUP -/-: embryonic day 18.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS26: tongue epithelium Strong Regionally restricted 2A FUP -/- Strong expression in epithelial cells, but taste bud did not appear onion-shaped.
Specimen 2A CVP +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: circumvallate papillae Present 2A CVP +/+
TS26: von Ebner's gland Present 2A CVP +/+
Specimen 2A CVP -/-: embryonic day 18.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS26: circumvallate papillae Present 2A CVP -/- Levels of expression in trenches and epithelium appeared unaffected compared to wild type.
TS26: von Ebner's gland Present 2A CVP -/- Expression in von Ebner's glands appear unaffected compared to wild type.
Specimen 2A FOP +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: foliate papillae Present 2A FOP +/+
TS26: von Ebner's gland Present 2A FOP +/+
Specimen 2A FOP -/-: embryonic day 18.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS26: foliate papillae Present 2A FOP -/- Levels of expression in trenches and epithelium appeared unaffected compared to wild type.
TS26: von Ebner's gland Present 2A FOP -/- Expression in von Ebner's glands appear unaffected compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory