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Gene Expression Data
Assay Details
Assay
Reference: J:335760 Zhang T, et al., The role of Eya1 and Eya2 in the taste system of mice from embryonic stage to adulthood. Front Cell Dev Biol. 2023;11:1126968
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7486068
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-TUBB3 (66375-1-Ig)
Detection system: Secondary antibody
Results
Specimen S1D +/+: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: facial nerve Present Regionally restricted S1D +/+ Expression in cranial nerves in association with papilla and trenches.
TS23: fungiform papillae Present Regionally restricted S1D +/+ Expression in cranial nerves in association with papilla and trenches.
Specimen S1D -/-: embryonic day 15.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS23: facial nerve Weak Regionally restricted S1D -/- Nerve contact reduced or absent. Only a few nerve fibers in region.
TS23: fungiform papillae Weak Regionally restricted S1D -/- Nerve contact reduced or absent. Only a few nerve fibers in region.
Specimen S1E +/+: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: circumvallate papillae Present Regionally restricted S1E +/+ Expression in cranial nerves in association with papilla and trenches.
TS23: glossopharyngeal nerve Present Regionally restricted S1E +/+ Expression in cranial nerves in association with papilla and trenches.
Specimen S1E -/-: embryonic day 15.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS23: circumvallate papillae Trace Regionally restricted S1E -/- Significantly fewer nerve fibers. Nerve contact reduced or absent.
TS23: glossopharyngeal nerve Trace Regionally restricted S1E -/- Significantly fewer nerve fibers. Nerve contact reduced or absent.
Specimen S1F +/+: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: foliate papillae Present Regionally restricted S1F +/+ Expression in cranial nerves in association with papilla and trenches.
TS23: glossopharyngeal nerve Present Regionally restricted S1F +/+ Expression in cranial nerves in association with papilla and trenches.
Specimen S1F -/-: embryonic day 15.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS23: foliate papillae Trace S1F -/- Significantly fewer nerve fibers. Nerve contact reduced or absent.
TS23: glossopharyngeal nerve Trace S1F -/- Significantly fewer nerve fibers. Nerve contact reduced or absent.
Specimen 1C FUP +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: facial nerve Present Regionally restricted 1C FUP +/+ Expression in cranial nerves in association with papilla and trenches. Fully innervated by nerve fibers by E18.5.
TS26: fungiform papillae Present Regionally restricted 1C FUP +/+ Expression in cranial nerves in association with papilla and trenches. Fully innervated by nerve fibers by E18.5.
Specimen 1C FUP -/-: embryonic day 18.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS26: facial nerve Weak Regionally restricted 1C FUP -/- Nerve contact reduced or absent. Only a few nerve fibers in region.
TS26: fungiform papillae Weak Regionally restricted 1C FUP -/- Nerve contact reduced or absent. Only a few nerve fibers in region.
Specimen 1E CVP +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: circumvallate papillae Present Regionally restricted 1E CVP +/+ Expression in cranial nerves in association with papilla and trenches.
TS26: glossopharyngeal nerve Present Regionally restricted 1E CVP +/+ Expression in cranial nerves in association with papilla and trenches.
Specimen 1E CVP -/-: embryonic day 18.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS26: circumvallate papillae Trace Regionally restricted 1E CVP -/- Significantly fewer nerve fibers. Nerve contact reduced or absent.
TS26: glossopharyngeal nerve Trace Regionally restricted 1E CVP -/- Significantly fewer nerve fibers. Nerve contact reduced or absent.
Specimen 1E FOP +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: foliate papillae Present Regionally restricted 1E FOP +/+ Expression in cranial nerves in association with papilla and trenches.
TS26: glossopharyngeal nerve Present Regionally restricted 1E FOP +/+ Expression in cranial nerves in association with papilla and trenches.
Specimen 1E FOP -/-: embryonic day 18.5; Eya1tm1Rilm/Eya1tm1Rilm (more )
Structure Level Pattern Image Note
TS26: foliate papillae Trace 1E FOP -/- Significantly fewer nerve fibers. Nerve contact reduced or absent.
TS26: glossopharyngeal nerve Trace 1E FOP -/- Significantly fewer nerve fibers. Nerve contact reduced or absent.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory