Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Col1a1-Mgp*)3EDKry
Name:	transgene insertion 3ED, Gerard Karsenty
MGI ID:	MGI:7484120
Synonyms:	alpha1(I)Col-Mgpm1
Transgene:	Tg(Col1a1-Mgp*)3EDKry  Location: unknown
Alliance:	Tg(Col1a1-Mgp*)3EDKry page

Strain of Origin:

Not Applicable

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Col1a1-Mgp*)3EDKry expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Mgp (MGI:96976) mouse promoter, modified mouse cDNA (p.E60D, p.E67D, p.E71D)   Tg(Col1a1-Mgp*)3EDKry expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Col1a1 (MGI:88467)   Mutation details: The transgene insert contains the following elements: 2.3 kb mouse Col1a1 gene proximal promoter sequence, modified mouse Mgp cDNA and SV40 poly(A) signal sequences. The modification involves changing glutamic acid codons 60, 67 and 71 (GAA, GAG, GAG) to aspartic acid (p.E60D, p.E67D, p.E71D). (J:335627)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:335627 Murshed M, et al., Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins. J Cell Biol. 2004 Jun 7;165(5):625-30
All:	1 reference(s)