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Gene Expression Data
Assay Details
Assay
Reference: J:256230 Shin SW, et al., Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Nat Commun. 2017 Nov 21;8(1):1643
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482807
Gene symbol: Cltc
Gene name: clathrin heavy chain
Antibody: anti-Clathrin heavy chain (ab21679)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen S4b CHC WT: embryonic day 0.5 (more )
Note: Double labeled: green - Cltc (CHC); red - phalloidin.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present S4b WT Merge (left) inset , S4b WT Merge (left) , S4b WT Merge (right) inset , S4b WT CHC , S4b WT Merge (right) , S4b WT CHC inset

Specimen S4b CHC KO: embryonic day 0.5; Dppa3tm1Masu/Dppa3tm1Masu (more )
Note: Double labeled: green - Cltc (CHC); red - phalloidin.
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present Regionally restricted S4b KO Merge (left) inset , S4b KO CHC inset , S4b KO CHC , S4b KO Merge (right) , S4b KO Merge (left) , S4b KO Merge (right) inset Expression in outer membranes of abnormally aggregated vesicles.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory